SCHEMBL631840

SCHEMBL631840

N=C(N)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.59
SIRT2 Q8IXJ6 2/20 0.59
SIRT1 Q96EB6 1/20 0.59
ITGB3 P05106 2/20 0.58
ITGAV P06756 2/20 0.58
TGM2 P21980 8/20 0.53
CPB1 P15086 1/20 0.52
CPB2 Q96IY4 1/20 0.52
CTSL P07711 2/20 0.52
CTSS P25774 1/20 0.52
SIRT5 Q9NXA8 1/20 0.52
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
CAPN1 P07384 1/20 0.50
CAPN2 P17655 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145708 1.00 FOLH1 (0.59) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL6768020 1.00 FOLH1 (0.59) FOLH1SIRT2SIRT1ITGB3ITGAV
Water SCHEMBL7266301 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL29401494 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL333888 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Water SCHEMBL7274005 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL333889 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Bromide SCHEMBL9221277 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL11411256 0.96 CTSL (0.56) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL9500591 0.93 SIRT2 (0.54) FOLH1SIRT2SIRT1ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162255-B Charge-convertible dendrimer and preparation method thereof 东莞理工学院 2024-07-09 CN claimed
CN-116726241-B Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-10-20 CN claimed
CN-116726241-A Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-09-12 CN claimed
CN-116162255-A Charge-convertible dendrimer and preparation method thereof 东莞理工学院 2023-05-26 CN claimed
CN-113845586-B Method for liquid-phase synthesis of acetyl hexapeptide-8 汉肽生物医药集团有限公司 2023-04-07 CN claimed
CN-110041407-B Method for synthesizing dessertraline acetate based on Fmoc dipeptide 南京肽业生物科技有限公司 2022-10-28 CN claimed
CN-111760473-A Composite semipermeable membrane, preparation method and application 中国石油化工股份有限公司 2020-10-13 CN claimed
CN-111760472-A Composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2020-10-13 CN claimed
CN-110339183-B Preparation method of cellulose-based poorly water-soluble or slightly water-soluble drug sustained-release microspheres 厦门大学 2020-08-11 CN claimed
US-6372895-B1 USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY 2002-04-16 US claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP claimed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0526877-A2 Peptide aldehydes as antithrombotic agents Bristol-Myers Squibb Company (US) 1993-02-10 EP claimed
JP-59203493-A None JP disclosed
WO-1984003507-A1 ENZYME INHIBITION FERRING AB (SE) 1984-09-13 WO disclosed
US-4108855-A Compounds of ergolene and ergoline structure and method for the preparation thereof RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1978-08-22 US disclosed