SCHEMBL6768020

SCHEMBL6768020

N=C(N)NCCC[C@@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.59
SIRT2 Q8IXJ6 2/20 0.59
SIRT1 Q96EB6 1/20 0.59
ITGB3 P05106 2/20 0.58
ITGAV P06756 2/20 0.58
TGM2 P21980 8/20 0.53
CPB1 P15086 1/20 0.52
CPB2 Q96IY4 1/20 0.52
CTSL P07711 2/20 0.52
CTSS P25774 1/20 0.52
SIRT5 Q9NXA8 1/20 0.52
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
CAPN1 P07384 1/20 0.50
CAPN2 P17655 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631840 1.00 FOLH1 (0.59) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL5145708 1.00 FOLH1 (0.59) FOLH1SIRT2SIRT1ITGB3ITGAV
Water SCHEMBL7266301 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL29401494 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL333888 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Water SCHEMBL7274005 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Hydrochloric Acid SCHEMBL333889 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
Bromide SCHEMBL9221277 0.99 FOLH1 (0.58) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL11411256 0.96 CTSL (0.56) FOLH1SIRT2SIRT1ITGB3ITGAV
SCHEMBL9500591 0.93 SIRT2 (0.54) FOLH1SIRT2SIRT1ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-6716843-B2 INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV LES LABORATOIRES SERVIER (FR) 2004-04-06 US disclosed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US disclosed
EP-1245568-A1 Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) Les Laboratoires Servier (FR) 2002-10-02 EP disclosed
US-5919765-A USING A (DI- OR TRI)PEPTIDES COR THERAPEUTICS, INC. (US) 1999-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087950-A1 New alpha-amino acid sulphonyl compounds DNPEP, DPP4, DPP7 FOLH1 481/4885SIRT2 896/4885SIRT1 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.