Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031505 | 0.93 | MAPT (0.58) | MAPTKMT2AGAAL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8781907 | 0.91 | MAPT (0.57) | MAPTKMT2AGAAL3MBTL1LMNA | |
| SCHEMBL10506137 | 0.82 | MEN1 (0.58) | MAPTKMT2APARP10ALDH1A1HPGD | |
| SCHEMBL12417136 | 0.79 | S100B (0.60) | MAPTKMT2AGAAL3MBTL1CA1 | |
| SCHEMBL246234 | 0.78 | ALDH1A1 (0.54) | KMT2APARP10ALDH1A1HPGDMEN1 | |
| SCHEMBL27497091 | 0.78 | MEN1 (0.47) | MAPTKMT2AAOC3ALDH1A1HPGD | |
| SCHEMBL171832 | 0.77 | WDR5 (0.66) | MAPTKMT2AGAAL3MBTL1LMNA | |
| SCHEMBL9811886 | 0.77 | MEN1 (0.50) | MAPTKMT2APARP10ALDH1A1HPGD | |
| SCHEMBL1818582 | 0.77 | LMNA (0.50) | MAPTKMT2AGAAL3MBTL1LMNA | |
| SCHEMBL6377733 | 0.77 | PARP10 (0.66) | MAPTKMT2ALMNAPARP10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562947-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2005-08-17 | — | — | EP | claimed |
| WO-2004043962-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2004-05-27 | — | — | WO | claimed |
| EP-1562947-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043962-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2004-05-27 | — | — | WO | disclosed |