Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863795 | 0.82 | MAPT (0.41) | HTTMAPTTSHRHSD17B10L3MBTL1 | |
| SCHEMBL2159922 | 0.80 | MAOA (0.39) | MAPTTSHRELOVL1PDE10ALMNA | |
| SCHEMBL474655 | 0.78 | MAPK1 (0.40) | HTTMAPTTSHRHSD17B10GAA | |
| Water SCHEMBL7847845 | 0.78 | MAOA (0.38) | MAPTTSHRELOVL1PDE10ALMNA | |
| SCHEMBL13662724 | 0.78 | NOTUM (0.47) | CYP2C9HTTMAPTTSHRHSD17B10 | |
| SCHEMBL2159964 | 0.78 | KMT2A (0.49) | HTTMAPTL3MBTL1MPOTPO | |
| SCHEMBL1800762 | 0.78 | PKM (0.48) | HTTMAPTL3MBTL1CYP3A4GAA | |
| SCHEMBL16651959 | 0.78 | CYP2A6 (0.49) | CYP2C9HTTL3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL17261505 | 0.77 | CYP2C9 (0.47) | CYP2C9HTTMAPTTSHRHSD17B10 | |
| SCHEMBL2360049 | 0.77 | KEAP1 (0.53) | MAPTL3MBTL1ADORA2AADORA1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112663064-A | Copper-molybdenum metal etching solution and preparation method and application thereof | 江苏艾森半导体材料股份有限公司 | 2021-04-16 | — | — | CN | claimed |
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | claimed |
| US-8470820-B2 | Nitrogen-containing heteroaryl derivatives | HOFFMAN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | claimed |
| EP-0138149-B1 | 5-ACYLAMINO-1-PHENYL PYRAZOLES | BAYER AG (DE) | 1989-01-18 | — | — | EP | claimed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | claimed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | claimed |
| US-4149005-A | Process for preparing 1-phenyl-3-aminopyrazoles | MONTEDISON S.P.A. (IT) | 1979-04-10 | — | — | US | claimed |
| JP-8208620-A | — | — | None | — | — | JP | disclosed |
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4656638-A2 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2025-12-03 | — | — | EP | disclosed |
| US-12384773-B2 | Thiazole compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| WO-2025096979-A1 | THIAZOLE COMPOUNDS AS KIT INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-3971771-A | DYES FOR POLYESTERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
| US-3954398-A | Polyester fibers dyed with a disazo disperse dyestuff | CIBA-GEIGY AG (CH) | 1976-05-04 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384773-B2 | Thiazole compounds and methods of use thereof | TPMT, CYP11B2, ABAT | CYP2C9 277/4885HTT 515/4885MAPT 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.