Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.61 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 2/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321254 | 0.86 | MAP3K5 (0.57) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL3305057 | 0.80 | PIN1 (0.76) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL6318891 | 0.77 | EGFR (0.41) | MAP3K5PIN1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL94363 | 0.77 | MAP3K5 (1.00) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL9346526 | 0.75 | MAP3K5 (0.72) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL16758710 | 0.73 | MAP3K5 (0.69) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL320850 | 0.71 | PDPK1 (0.66) | MAP3K5PIN1CYP1A2PDPK1GDA | |
| SCHEMBL7806465 | 0.70 | PIN1 (0.60) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL2891519 | 0.70 | MAP3K5 (0.64) | MAP3K5PIN1POLBCYP2C19CYP1A2 | |
| SCHEMBL3297931 | 0.69 | PIN1 (1.00) | PIN1CYP2C19CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215787-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215787-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURINES | PNP, HPRT1, NUDT1 | MAP3K5 3423/4885PIN1 4378/4885POLB 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.