SCHEMBL6319913

SCHEMBL6319913

Nc1c(Cl)cccc1C(F)(c1cccc(Cl)c1N)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
NR4A2 P43354 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
PDK1 Q15118 1/20 0.30
PDK2 Q15119 1/20 0.30
PDK3 Q15120 1/20 0.30
PDK4 Q16654 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9617287 0.82 CD44 (0.38) ALDH1A1TSHRPDK2
SCHEMBL9770062 0.80 TSHR (0.37) KCNN4ALDH1A1TSHRPDK1PDK2
SCHEMBL3675546 0.79 KCNN4 (0.42) KCNN4ALDH1A1TSHRPDK1PDK2
SCHEMBL1000973 0.79 P2RX7 (0.40) KCNN4NR4A2ALDH1A1TSHR
SCHEMBL31571903 0.79 P2RX7 (0.40) KCNN4NR4A2ALDH1A1TSHR
SCHEMBL689225 0.77 G6PD (0.37) ALDH1A1TSHR
SCHEMBL6319918 0.77 P2RX7 (0.33) NR4A2ALDH1A1TSHRPDK2
SCHEMBL3678117 0.74 KCNN4 (0.41) KCNN4ALDH1A1TSHRPDK1PDK2
SCHEMBL6320731 0.73 GABRA1 (0.39) PDK2
SCHEMBL3676254 0.72 KCNN4 (0.39) KCNN4ALDH1A1TSHRPDK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296540-B1 DISPLAY TORAY INDUSTRIES (JP) 2019-10-16 EP disclosed
US-6887643-B2 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-05-03 US disclosed
US-20040053156-A1 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2004-03-18 US disclosed
US-6696112-B2 POSITIVE-TYPE, PHOTOSENSITIVITY; FLAT PANEL DISPLAYS TORAY INDUSTRIES, INC. (JP) 2004-02-24 US disclosed
EP-1388758-A1 Photosensitive heat resistant resin precursor composition TORAY INDUSTRIES, INC. (JP) 2004-02-11 EP disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed