SCHEMBL6320731

SCHEMBL6320731

CCc1cccc(C(F)(c2cccc(CC)c2N)C(F)(F)C(F)(F)F)c1N

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.39
GABRB2 P47870 4/20 0.39
PDK2 Q15119 1/20 0.33
IDO1 P14902 2/20 0.33
CACNA1C Q13936 1/20 0.31
SCN5A Q14524 1/20 0.31
ATP4A P20648 1/20 0.31
ATP4B P51164 1/20 0.31
HSD11B1 P28845 1/20 0.31
ELANE P08246 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861905 0.82 GABRA1 (0.45) GABRA1GABRB2PDK2IDO1CACNA1C
SCHEMBL6312713 0.78
SCHEMBL9617287 0.77 CD44 (0.38) PDK2LMNASMN1; SMN2
SCHEMBL10613733 0.76 GABRA1 (0.46) GABRA1GABRB2ATP4AATP4BELANE
SCHEMBL689225 0.73 G6PD (0.37) LMNASMN1; SMN2
SCHEMBL6319913 0.73 KCNN4 (0.33) PDK2
SCHEMBL1332031 0.72 GABRA1 (0.55) GABRA1GABRB2PDK2CACNA1CSCN5A
SCHEMBL262868 0.72 GABRA1 (0.55) GABRA1GABRB2PDK2CACNA1CSCN5A
SCHEMBL6319928 0.71 IDO1 (0.40) IDO1
SCHEMBL28967677 0.70 GABRA1 (0.52) GABRA1GABRB2PDK2CACNA1CSCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296540-B1 DISPLAY TORAY INDUSTRIES (JP) 2019-10-16 EP disclosed
US-6887643-B2 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-05-03 US disclosed
EP-0878740-B1 Radiation sensitive polymer composition TORAY INDUSTRIES (JP) 2004-11-10 EP disclosed
US-20040053156-A1 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2004-03-18 US disclosed
US-6696112-B2 POSITIVE-TYPE, PHOTOSENSITIVITY; FLAT PANEL DISPLAYS TORAY INDUSTRIES, INC. (JP) 2004-02-24 US disclosed
EP-1388758-A1 Photosensitive heat resistant resin precursor composition TORAY INDUSTRIES, INC. (JP) 2004-02-11 EP disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
US-6090525-A PHOTOSENSITIVE POLYIMIDE COATING AGENT COMPOSITION WITH BOTH GOOD VISCOSITY STABILITY AT ROOM TEMPERATURE WITH LAPSE OF TIME AND GOOD PHOTOSENSITIVE PERFORMANCE TORAY INDUSTRIES, INC. (JP) 2000-07-18 US disclosed
EP-0878740-A1 Radiation sensitive polymer composition TORAY INDUSTRIES, INC. (JP) 1998-11-18 EP disclosed