SCHEMBL6320160

SCHEMBL6320160

CC(C)C[CH]c1ccc([CH]CC(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.39
ALDH1A3 P47895 2/20 0.34
HTR2A P28223 3/20 0.32
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALDH3A1 P30838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436098 0.88 HSD17B10 (0.46) TYRCYP2A6ALDH1A1
SCHEMBL543436 0.87 HTR2A (0.47) HTR2ACYP2A6ALDH1A1
SCHEMBL7459654 0.76 ALDH1A1 (0.48) HTR2ACYP2A6ALDH1A1
SCHEMBL11170926 0.74 MAPT (0.39) ALDH1A1
SCHEMBL15662895 0.74 ALOX5 (0.38) ALDH1A1
SCHEMBL4351016 0.67 HTR2A (0.64) HTR2ACYP2A6
SCHEMBL6028571 0.67 HTR2A (0.44) HTR2ACYP2A6ALDH1A1
SCHEMBL9443976 0.67 PTGS1 (0.42) HTR2AALDH1A1
SCHEMBL8166743 0.66 HTR2A (0.42) HTR2ACYP2A6ALDH1A1
SCHEMBL11027746 0.66 GRIK1 (0.49) HTR2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6906226-B2 Hydroxymethyl-substituted polyfunctional phenols HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-06-14 US disclosed