Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.60 |
| ▸ | CTSS | P25774 | 12/20 | 0.60 |
| ▸ | CTSB | P07858 | 9/20 | 0.59 |
| ▸ | CTSK | P43235 | 9/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311222 | 1.00 | CTSL (0.60) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL6311227 | 1.00 | CTSL (0.60) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL1152786 | 0.87 | ATM (0.56) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL16834866 | 0.87 | ATM (0.56) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL16846451 | 0.87 | ATM (0.56) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL7300987 | 0.87 | ATM (0.56) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL6311738 | 0.85 | CTSS (0.62) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL6311732 | 0.85 | CTSS (0.62) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL6312473 | 0.85 | CTSS (0.62) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL16492789 | 0.83 | CTSS (0.60) | CTSLCTSSCTSBCTSKELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | CHO HIDETSURA | 2005-11-10 | — | — | US | disclosed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | disclosed |
| WO-2002014324-A2 | DIAZEPINONES AS ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | ZC3HAV1, ECI1, ZC3HAV1L | CTSL 4145/4885CTSS 2164/4885CTSB 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.