Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879474 | 1.00 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL10418116 | 0.88 | MAPT (0.63) | ALDH1A1SMN1; SMN2HPGDMAPK1MAPT | |
| SCHEMBL5311205 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL5031039 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL133738 | 0.81 | ALDH1A1 (0.87) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL21226237 | 0.80 | MAPT (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL10418143 | 0.80 | HDAC3 (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL6683314 | 0.79 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL2220646 | 0.78 | HDAC3 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL21133123 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215787-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215787-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURINES | PNP, HPRT1, NUDT1 | ALDH1A1 312/4885SMN1; SMN2 3101/4885KMT2A 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.