SCHEMBL879474

SCHEMBL879474

CSCC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
SMN1; SMN2 Q16637 5/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
HPGD P15428 4/20 0.56
MAPK1 P28482 3/20 0.56
MAPT P10636 3/20 0.56
CYP3A4 P08684 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
KDM4E B2RXH2 2/20 0.56
ALOX15 P16050 1/20 0.56
CES1 P23141 1/20 0.56
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6320924 1.00 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL10418116 0.88 MAPT (0.63) ALDH1A1SMN1; SMN2HPGDMAPK1MAPT
SCHEMBL5311205 0.83 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL5031039 0.81 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL133738 0.81 ALDH1A1 (0.87) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL21226237 0.80 MAPT (0.59) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL10418143 0.80 HDAC3 (0.62) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL6683314 0.79 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL2220646 0.78 HDAC3 (0.57) ALDH1A1SMN1; SMN2KMT2AMEN1MAPT
SCHEMBL21133123 0.78 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3661914-A1 PROCESS FOR THE PREPARATION OF ELAFIBRANOR AND NOVEL SYNTHESIS INTERMEDIATES Advitech Advisory and Technologies SA (CH) 2020-06-10 EP claimed
CN-107641112-B Synthetic method of 2-methylthio-1-phenyl-ethanone derivative 浙江工业大学 2020-05-22 CN claimed
CN-111183132-A Preparation method of Elafibranor and novel synthetic intermediate 阿德万泰克咨询与技术股份有限公司 2020-05-19 CN claimed
WO-2019025017-A1 PROCESS FOR THE PREPARATION OF ELAFIBRANOR AND NOVEL SYNTHESIS INTERMEDIATES ADVITECH ADVISORY AND TECHNOLOGIES SA (CH) 2019-02-07 WO claimed
US-7049459-B2 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2006-05-23 US claimed
US-20040242680-A1 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2004-12-02 US claimed
WO-2003030812-A2 1-[(4-METHYL THIO)PHENYL]-2-(PHENYL ACETOXY)-1-ETHANONE AND A PROCESS FOR PREPARING THE SAME SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2003-04-17 WO claimed
EP-0780380-B1 Triazole derivatives with antimycotic action and intermediates SS PHARMACEUTICAL CO (JP) 2001-06-13 EP claimed
EP-0798294-B1 Process for preparing alpha-haloacetophenone derivative SUMITOMO SEIKA CHEMICALS (JP) 2000-06-14 EP claimed
US-5986144-A Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient SS PHARMACEUTICAL CO., LTD. (JP) 1999-11-16 US claimed
US-5821388-A Process for preparing α-haloacetophenone derivative SUMITOMO SEIKA CHEMICAL CO., LTD. (JP) 1998-10-13 US claimed
EP-0798294-A2 Process for preparing haloacetophenone derivative SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-10-01 EP claimed
EP-0780380-A1 Triazole derivatives with antimycotic action and intermediates SS PHARMACEUTICAL CO., LTD. (JP) 1997-06-25 EP claimed
JP-9255653-A None JP disclosed
WO-2026102164-A1 COMPOSITIONS AND METHODS OF USE THEREOF BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-05-15 WO disclosed
EP-4553061-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-05-14 EP disclosed
US-4101583-A Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-07-18 US disclosed
US-4080341-A Carbazolenine and indole compounds THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-03-21 US disclosed
US-4067875-A Certain N-phenyl or N-pyridyl aza sulfonium salts THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-01-10 US disclosed
US-3992392-A Synthesis of indoles from anilines and intermediates therein THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242680-A1 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same PTGES2, PTGS2, CYP2J2 ALDH1A1 230/4885SMN1; SMN2 4675/4885KMT2A 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.