Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826082 | 0.81 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| SCHEMBL3698957 | 0.76 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| SCHEMBL8344401 | 0.76 | ACLY (0.38) | TSHRHIF1AALDH1A1 | |
| SCHEMBL9257550 | 0.75 | — | — | |
| SCHEMBL7819856 | 0.75 | — | — | |
| SCHEMBL7023611 | 0.75 | — | — | |
| SCHEMBL7834683 | 0.73 | LMNA (0.40) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| Hydrochloric Acid SCHEMBL9255230 | 0.73 | LMNA (0.40) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| SCHEMBL6337778 | 0.72 | APP (0.33) | — | |
| SCHEMBL8064464 | 0.71 | ALDH1A1 (0.40) | LMNAALKBH5SUCNR1EGLN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222461-A1 | Method for the production of substituted trifluoroethylenes | BAYER CROPSCIENCE AG (DE) | 2005-10-06 | — | — | US | disclosed |
| EP-1506150-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES | Bayer CropScience Aktiengesellschaft (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003095401-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-11-20 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| WO-1998024744-A1 | POLYHALOGEN HEXENES PRODUCTION THEREOF AND PRODUCTION OF HALOGENATED C4 CARBOXYLIC ACIDS FROM THESE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222461-A1 | Method for the production of substituted trifluoroethylenes | CBR3, HDHD5, CBR1 | LMNA 3839/4885ALKBH5 1087/4885SUCNR1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.