Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322935 | 1.00 | ESR1 (0.38) | ESR1ALDH1A1HSD11B1OPRK1CYP1A2 | |
| SCHEMBL6323872 | 0.81 | ADRA1A (0.49) | OPRK1CYP1A2CYP2C19ADRA1ALMNA | |
| SCHEMBL6320874 | 0.78 | BACE1 (0.41) | ALDH1A1OPRK1CYP1A2CYP2C19ADRA1A | |
| SCHEMBL6320867 | 0.78 | BACE1 (0.41) | ALDH1A1OPRK1CYP1A2CYP2C19ADRA1A | |
| Hydrochloric Acid SCHEMBL6328295 | 0.73 | ADRA1A (0.39) | HSD11B1OPRK1CYP1A2CYP2C19ADRA1A | |
| Hydrochloric Acid SCHEMBL6328292 | 0.73 | ADRA1A (0.39) | HSD11B1OPRK1CYP1A2CYP2C19ADRA1A | |
| Hydrochloric Acid SCHEMBL6320397 | 0.67 | POLB (0.53) | ESR1ALDH1A1CYP1A2CYP2C19ADRA1A | |
| Hydrochloric Acid SCHEMBL6327403 | 0.67 | POLB (0.53) | ESR1ALDH1A1CYP1A2CYP2C19ADRA1A | |
| SCHEMBL6642402 | 0.66 | ALDH1A1 (0.52) | ALDH1A1OPRK1ADRA1AGAAADRA2B | |
| SCHEMBL6642397 | 0.65 | ALDH1A1 (0.51) | ALDH1A1OPRK1ADRA1AGAAADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | ESR1 3038/4885ALDH1A1 197/4885HSD11B1 667/4885 |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | ESR1 3388/4885ALDH1A1 183/4885HSD11B1 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.