SCHEMBL6322973

SCHEMBL6322973

CCCNC(=O)c1ccccc1NC(=O)NS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
THRB P10828 2/20 0.65
LMNA P02545 2/20 0.65
NPSR1 Q6W5P4 2/20 0.65
CYP3A4 P08684 1/20 0.65
TSHR P16473 1/20 0.65
NFKB1 P19838 1/20 0.65
HTR2A P28223 1/20 0.65
CYP2C19 P33261 1/20 0.65
ADRA1A P35348 1/20 0.65
L3MBTL1 Q9Y468 4/20 0.58
FLT1 P17948 5/20 0.51
FLT4 P35916 5/20 0.51
KDR P35968 5/20 0.51
GAA P10253 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
KDM4E B2RXH2 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6330129 0.91 L3MBTL1 (0.63) ALDH1A1SMN1; SMN2THRBLMNANPSR1
SCHEMBL6325407 0.90 L3MBTL1 (0.59) ALDH1A1SMN1; SMN2THRBLMNANPSR1
SCHEMBL6329887 0.88 FBP1 (0.57) ALDH1A1SMN1; SMN2THRBLMNANPSR1
SCHEMBL6324572 0.82 FBP1 (0.60) ALDH1A1SMN1; SMN2L3MBTL1GAAKDM4E
SCHEMBL6322119 0.81 L3MBTL1 (0.59) ALDH1A1SMN1; SMN2LMNANPSR1TSHR
Chlorpropamide SCHEMBL1537108 0.80 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2THRBLMNANPSR1
Chlorpropamide SCHEMBL23947 0.80 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2THRBLMNANPSR1
Chlorpropamide SCHEMBL20770748 0.80 ALDH1A1 (0.82) ALDH1A1SMN1; SMN2THRBLMNANPSR1
SCHEMBL6331436 0.79 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2THRBLMNANPSR1
Chlorpropamide SCHEMBL28353575 0.79 ALDH1A1 (0.97) ALDH1A1SMN1; SMN2THRBLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed