Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323155 | 1.00 | TSHR (0.40) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL27528726 | 0.79 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL26273500 | 0.79 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6325788 | 0.78 | LMNA (0.38) | TSHRCETPMAPTHTTALDH1A1 | |
| SCHEMBL1532632 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL16190580 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL195939 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL6325792 | 0.78 | LMNA (0.38) | TSHRCETPMAPTHTTALDH1A1 | |
| SCHEMBL6342061 | 0.77 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6382635 | 0.77 | F2 (0.33) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |