Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325788 | 1.00 | LMNA (0.38) | LMNATSHRCETPMMP1MMP2 | |
| SCHEMBL6322467 | 0.80 | LMNA (0.37) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL6322477 | 0.80 | LMNA (0.37) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL28728748 | 0.79 | CETP (0.39) | CETPHTT | |
| SCHEMBL6323155 | 0.78 | TSHR (0.40) | LMNATSHRCETPMAPTALDH1A1 | |
| SCHEMBL6323156 | 0.78 | TSHR (0.40) | LMNATSHRCETPMAPTALDH1A1 | |
| SCHEMBL6321649 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL6321655 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL195939 | 0.75 | GAA (0.44) | LMNATSHRCETPCYP2D6ALDH1A1 | |
| SCHEMBL1532632 | 0.75 | GAA (0.44) | LMNATSHRCETPCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |