Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323156 | 1.00 | TSHR (0.40) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL27528726 | 0.79 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL26273500 | 0.79 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6325788 | 0.78 | LMNA (0.38) | TSHRCETPMAPTHTTALDH1A1 | |
| SCHEMBL1532632 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL16190580 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL195939 | 0.78 | GAA (0.44) | TSHRHSD17B10CETPMGAMGAA | |
| SCHEMBL6325792 | 0.78 | LMNA (0.38) | TSHRCETPMAPTHTTALDH1A1 | |
| SCHEMBL6342061 | 0.77 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6382635 | 0.77 | F2 (0.33) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332392-B1 | Dioxane liquid crystal compounds | SHOWA SHELL SEKIYU (JP) | 1994-12-07 | — | — | EP | claimed |
| EP-0332392-A2 | Dioxane liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-09-13 | — | — | EP | claimed |
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
| CN-112645890-B | Synthesis method of 2-pyrazine carboxylic ester compound | 江苏广域化学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3973997-A1 | MEMBRANE ACTIVE MOLECULES | Branequest, Inc. (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-112645890-A | Synthesis method of 2-pyrazine carboxylic ester compound | 江苏广域化学有限公司 | 2021-04-13 | — | — | CN | disclosed |
| WO-2020148780-A1 | PROCESS FOR PREPARATION OF 4,4,4- TRIFLUOROBUT-2-EN-1-OL AND INTERMEDIATE THEREOF | SRF LIMITED (IN) | 2020-07-23 | — | — | WO | disclosed |
| EP-1258470-B1 | Process for producing optically active alcohol | TAKASAGO PERFUMERY CO LTD (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |
| US-6723871-B2 | ASYMMETRIC REDUCTION OF A BETA-KETO ESTER IN THE PRESENCE OF A RUTHENIUM-DIAMINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030004362-A1 | Process for producing optically active alcohol | TAKASAGO INTERNATIONAL CORPORATION | 2003-01-02 | — | — | US | disclosed |
| US-5171471-A | Having wide range of phase transition temperatures for faster optical response times | SHOWA SHELL SEKIYU K.K. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0404584-A2 | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404586-A2 | Nitrogen deprotected 4-acyloxyazetidin-2-ones | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404583-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404585-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4952288-A | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO., INC. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4940520-A | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO., INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4923982-A | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO., INC. (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0332392-A2 | Dioxane liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | IL1R1, LRBA, HCAR1 | TSHR 2127/4885HSD17B10 348/4885CETP 3531/4885 |
| US-20030004362-A1 | Process for producing optically active alcohol | ADH1A, ADH5, ADH1C | TSHR 1206/4885HSD17B10 103/4885CETP 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.