Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316631 | 0.78 | PGR (0.47) | PGRCYP11B1CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL10590671 | 0.74 | PGR (0.51) | PGRMAP3K14CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL27719379 | 0.73 | CYP11B2 (0.43) | PGRMAP3K14CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL9906167 | 0.73 | KDM1A (0.49) | PGRBRD4ADORA3AKR1C1 | |
| SCHEMBL19130584 | 0.68 | HDAC9 (0.50) | PGRMAP3K14CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL5796055 | 0.68 | HDAC9 (0.50) | PGRMAP3K14CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL7308988 | 0.68 | CYP2C9 (0.44) | PGRAKR1C1 | |
| SCHEMBL31285786 | 0.68 | CASR (0.38) | PGRCYP11B1CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL10904978 | 0.68 | PGR (0.40) | PGRMAP3K14CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL7072344 | 0.66 | SLC18A3 (0.43) | PGRCYP11B1CYP11B2CYP3A4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6974855-B1 | Polyimides by photochemical cyclopolymerization | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-12-13 | — | — | US | disclosed |