SCHEMBL6316631

SCHEMBL6316631

OC1(c2ccccc2)CCCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.47
KDM1A O60341 3/20 0.46
HDAC9 Q9UKV0 1/20 0.45
CYP3A4 P08684 3/20 0.43
SIGMAR1 Q99720 3/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
DRD2 P14416 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTR2B P41595 1/20 0.43
MTOR P42345 1/20 0.43
AKR1B1 P15121 1/20 0.42
CYP17A1 P05093 2/20 0.42
CYP11B1 P15538 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906167 0.94 KDM1A (0.49) PGRKDM1AHDAC9SIGMAR1TSHR
SCHEMBL19130584 0.90 HDAC9 (0.50) PGRKDM1AHDAC9CYP3A4SIGMAR1
SCHEMBL5796055 0.90 HDAC9 (0.50) PGRKDM1AHDAC9CYP3A4SIGMAR1
SCHEMBL4133169 0.86 CYP3A4 (0.58) PGRKDM1ACYP3A4SIGMAR1AKR1B1
SCHEMBL7072344 0.82 SLC18A3 (0.43) PGRKDM1AHDAC9CYP3A4SIGMAR1
SCHEMBL7321561 0.82 SIGMAR1 (0.51) KDM1ACYP3A4SIGMAR1AKR1B1CYP11B1
SCHEMBL13599735 0.82 PGR (0.49) PGRKDM1ACYP3A4AKR1B1CYP17A1
SCHEMBL10590671 0.81 PGR (0.51) PGRCYP3A4SIGMAR1DRD2CYP17A1
SCHEMBL7885283 0.78 BRD4 (0.40) KDM1AHDAC9CYP3A4TP53TSHR
SCHEMBL4195493 0.78 KDM1A (0.50) KDM1AHDAC9CYP3A4SIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894146-B Synthesis method of 3-bromo-1-phenyl naphthalene 上海固创化工新材料有限公司 2025-05-06 CN claimed
CN-115894146-A Synthetic method of 3-bromo-1-phenylnaphthalene 上海固创化工新材料有限公司 2023-04-04 CN claimed
CN-115894146-B Synthesis method of 3-bromo-1-phenyl naphthalene 上海固创化工新材料有限公司 2025-05-06 CN disclosed
CN-115894146-B Synthesis method of 3-bromo-1-phenyl naphthalene 上海固创化工新材料有限公司 2025-05-06 CN disclosed
WO-2025038899-A2 METHODS FOR CARBON DIOXIDE SEPARATION AND MATERIALS AND SYSTEMS FOR SAME CORNELL UNIVERSITY (US) 2025-02-20 WO disclosed
CN-115093308-B Synthesis method of 1-bromo-4-phenyl naphthalene 上海固创化工新材料有限公司 2024-03-22 CN disclosed
CN-115894146-A Synthetic method of 3-bromo-1-phenylnaphthalene 上海固创化工新材料有限公司 2023-04-04 CN disclosed
CN-115894146-A Synthetic method of 3-bromo-1-phenylnaphthalene 上海固创化工新材料有限公司 2023-04-04 CN disclosed
CN-115093308-A Synthesis method of 1-bromo-4-phenylnaphthalene 上海固创化工新材料有限公司 2022-09-23 CN disclosed
US-20140088303-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL SEKISUI MEDICAL CO., LTD. (JP) 2014-03-27 US disclosed
US-20140088303-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL SEKISUI MEDICAL CO., LTD. (JP) 2014-03-27 US disclosed
US-8198445-B2 Phosphoramide compound, method for producing the same, ligand, complex, catalyst and method for producing optically active alcohol NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2012-06-12 US disclosed
US-8198445-B2 Phosphoramide compound, method for producing the same, ligand, complex, catalyst and method for producing optically active alcohol NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2012-06-12 US disclosed
US-20100113786-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-05-06 US disclosed
US-20100113786-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-05-06 US disclosed
EP-2128167-A1 PHOSPHOROAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL National University Corporation Nagoya University (JP) 2009-12-02 EP disclosed
US-6974855-B1 Polyimides by photochemical cyclopolymerization THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2005-12-13 US disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
US-3947520-A Compounds and process for preparing the same THE UPJOHN COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113786-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1C, ADH1A, DERA PGR 2882/4885KDM1A 3189/4885HDAC9 1090/4885
US-20140088303-A1 PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1C, ADH1A, DERA PGR 2882/4885KDM1A 3189/4885HDAC9 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.