Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200370 | 0.84 | BACE1 (0.47) | BACE1GAAMAPTCA12CA1 | |
| Pyrimidine SCHEMBL9443954 | 0.82 | HSP90AA1 (0.34) | GAAMAPTALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10494933 | 0.81 | BACE1 (0.44) | BACE1GAAMAPTCA12CA1 | |
| SCHEMBL67497 | 0.77 | BACE1 (0.54) | BACE1MAPTCA12CA1CA2 | |
| SCHEMBL29433138 | 0.77 | BACE1 (0.39) | BACE1GAAMAPTCA12CA1 | |
| SCHEMBL16414395 | 0.77 | ALOX15 (0.48) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL8222176 | 0.77 | THRB (0.43) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL766082 | 0.77 | BACE1 (0.39) | BACE1GAAMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL10383986 | 0.74 | CA12 (0.37) | BACE1GAAMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL28229048 | 0.74 | THRB (0.42) | GAAMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585814-B1 | FARNESYL DIBENZODIAZEPINONES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | THALLION PHARMACEUTICALS INC (CA) | 2014-05-07 | — | — | EP | disclosed |
| EP-1866357-B1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO KK (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-8044235-B2 | (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof | SHOWA DENKO K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20090263886-A1 | FARNESYL DIBENZODIAZEPINONE AND PROCESSES FOR ITS PRODUCTION | THALLION PHARMACEUTICALS INC. | 2009-10-22 | — | — | US | disclosed |
| US-7521222-B2 | Farnesyl dibenzodiazepinone and processes for its production | THALLION PHARMACEUTICALS, INC. (CA) | 2009-04-21 | — | — | US | disclosed |
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | SHOWA DENKO K.K. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20080199940-A1 | Farnesyl dibenzodiazepinone and processes for its production | ECOPIA BIOSCIENCES, INC. (CA) | 2008-08-21 | — | — | US | disclosed |
| US-20080131943-A1 | POLYNUCLEOTIDES FOR PRODUCTION OF FARNESYL DIBENZODIAZEPINONES | THALLION PHARMACEUTICALS INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| US-7297524-B2 | Polynucleotides for production of farnesyl dibenzodiazepinones | THALLION PHARMCEUTICALS INC. (CA) | 2007-11-20 | — | — | US | disclosed |
| WO-2007102936-A2 | POLYNUCLEOTIDES FOR PRODUCTION OF FARNESYL DIBENZODIAZEPINONES | THALLION PHARMACEUTICALS INC. (CA) | 2007-09-13 | — | — | WO | disclosed |
| US-7101872-B2 | Farnesyl dibenzodiazepinone, and processes for its production | ECOPIA BIOSCIENCES, INC. (CA) | 2006-09-05 | — | — | US | disclosed |
| US-20060172395-A1 | Polynucleotides for production of farnesyl dibenzodiazepinones | ECOPIA BIOSCIENCES, INC. | 2006-08-03 | — | — | US | disclosed |
| EP-1585814-A1 | FARNESYL DIBENZODIAZEPINONES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | Ecopia Biosciences Inc. (CA) | 2005-10-19 | — | — | EP | disclosed |
| US-20050043297-A1 | Farnesyl dibenzodiazepinone, processes for its production and its use as a pharmaceutical | ECOPIA BIOSCIENCES, INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2004065591-A1 | FARNESYL DIBENZODIAZEPINONES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | ECOPIA BIOSCIENCES INC. (CA) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263886-A1 | FARNESYL DIBENZODIAZEPINONE AND PROCESSES FOR ITS PRODUCTION | FDPS, GGPS1, FNTB | BACE1 2994/4885GAA 3334/4885MAPT 4775/4885 |
| US-20050043297-A1 | Farnesyl dibenzodiazepinone, processes for its production and its use as a pharmaceutical | FDPS, GGPS1, FNTB | BACE1 3267/4885GAA 3646/4885MAPT 4823/4885 |
| US-20060172395-A1 | Polynucleotides for production of farnesyl dibenzodiazepinones | FDPS, FNTA, FNTB | BACE1 3093/4885GAA 3382/4885MAPT 4483/4885 |
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | PRMT5, ACR, PRMT1 | BACE1 4061/4885GAA 4351/4885MAPT 1321/4885 |
| US-20080199940-A1 | Farnesyl dibenzodiazepinone and processes for its production | FDPS, GGPS1, FNTB | BACE1 3018/4885GAA 3213/4885MAPT 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.