Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.77 |
| ▸ | DRD1 | P21728 | 2/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.77 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012454 | 1.00 | DRD2 (0.77) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL30012562 | 0.94 | DRD2 (0.74) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL3292837 | 0.94 | DRD2 (0.74) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL43719 | 0.87 | TAAR1 (1.00) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL29465557 | 0.87 | TAAR1 (1.00) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL31674607 | 0.87 | DRD2 (0.68) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL11232474 | 0.87 | DRD2 (0.68) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| SCHEMBL28368586 | 0.87 | DRD2 (0.68) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| Bromide SCHEMBL3284467 | 0.85 | TAAR1 (0.96) | DRD2DRD1TAAR1ENPP2CHRM2 | |
| Hydrochloric Acid SCHEMBL453247 | 0.85 | TAAR1 (0.96) | DRD2DRD1TAAR1ENPP2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115228290-A | Preparation method of cleaning-resistant reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| EP-1347752-A4 | ANTI-PROLIFERATIVE DRUGS | UNIV RAMOT (IL) | 2005-04-06 | — | — | EP | claimed |
| US-20050013853-A1 | Anti-proliferative drugs | PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) | 2005-01-20 | — | — | US | claimed |
| US-20040029860-A1 | Anti-proliferative drugs | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2004-02-12 | — | — | US | claimed |
| EP-1347752-A2 | ANTI-PROLIFERATIVE DRUGS | Ramot at Tel-Aviv University Ltd. (IL) | 2003-10-01 | — | — | EP | claimed |
| WO-2002043652-A2 | ANTI-PROLIFERATIVE DRUGS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2002-06-06 | — | — | WO | claimed |
| US-6384031-B1 | — | — | None | — | — | US | disclosed |
| CN-115228290-A | Preparation method of cleaning-resistant reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| US-20220117937-A1 | USE OF SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION IN BIOFILMS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2022-04-21 | — | — | US | disclosed |
| EP-2806897-B1 | INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1 | HOFFMANN LA ROCHE (CH) | 2017-08-02 | — | — | EP | disclosed |
| CN-103553945-B | Alkoxy compounds for disease treatment | ACUCELA INC | 2015-01-07 | — | — | CN | disclosed |
| CN-103553945-A | Alkoxy compounds for disease treatment | ACUCELA INC | 2014-02-05 | — | — | CN | disclosed |
| CN-101889017-B | Alkoxy compounds for the treatment of diseases | ACUCELA INC | 2013-11-27 | — | — | CN | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| US-5972939-A | Cyclopentene derivatives useful as antagonists of the motilin receptor | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| EP-0846679-A2 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |
| US-5011989-A | Asymmetric reducing agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0007716-A1 | R-N-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117937-A1 | USE OF SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION IN BIOFILMS | BLVRB, Q6ZSR9, BTD | DRD2 133/4885DRD1 112/4885TAAR1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.