Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | DRD1 | P21728 | 2/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD5 | P21918 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31674607 | 1.00 | DRD2 (0.68) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL2323457 | 0.98 | DRD2 (0.65) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL966461 | 0.95 | CALM1 (0.64) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL4949943 | 0.95 | DRD2 (0.63) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL11232474 | 0.95 | DRD2 (0.68) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL5542876 | 0.93 | OPRK1 (0.69) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL21002079 | 0.93 | MGLL (0.68) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL26548204 | 0.93 | MGLL (0.68) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL8398287 | 0.93 | MGLL (0.68) | DRD2DRD1TAAR1CALM1CHRM2 | |
| SCHEMBL723832 | 0.90 | DRD2 (0.74) | DRD2DRD1TAAR1CALM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110741041-A | Polyvinyl chloride and copolyester compositions and articles made using these compositions | 伊士曼化工公司 | 2020-01-31 | — | — | CN | disclosed |