SCHEMBL43719

SCHEMBL43719

NCCc1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 10/20 1.00
DRD2 P14416 3/20 1.00
DRD1 P21728 3/20 1.00
ENPP2 Q13822 1/20 0.68
CHRM2 P08172 1/20 0.57
CHRM1 P11229 1/20 0.57
CHRM3 P20309 1/20 0.57
MAPK1 P28482 3/20 0.55
ALOX15 P16050 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
PKM P14618 1/20 0.55
NFKB1 P19838 1/20 0.55
OPRK1 P41145 1/20 0.55
KDM4E B2RXH2 4/20 0.54
ADRA2A P08913 3/20 0.54
SLC6A2 P23975 3/20 0.54
ALDH1A1 P00352 2/20 0.54
HTR1A P08908 2/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29465557 1.00 TAAR1 (1.00) TAAR1DRD2DRD1ENPP2CHRM2
Bromide SCHEMBL3284467 0.98 TAAR1 (0.96) TAAR1DRD2DRD1ENPP2CHRM2
Bromide SCHEMBL30626448 0.98 TAAR1 (0.96) TAAR1DRD2DRD1ENPP2CHRM2
Hydrochloric Acid SCHEMBL31505864 0.98 TAAR1 (0.96) TAAR1DRD2DRD1ENPP2CHRM2
Hydrochloric Acid SCHEMBL453247 0.98 TAAR1 (0.96) TAAR1DRD2DRD1ENPP2CHRM2
Phenol SCHEMBL28853303 0.92 TAAR1 (0.85) TAAR1DRD2DRD1ENPP2CHRM2
SCHEMBL30012454 0.87 DRD2 (0.77) TAAR1DRD2DRD1ENPP2CHRM2
SCHEMBL632444 0.87 DRD2 (0.77) TAAR1DRD2DRD1ENPP2CHRM2
SCHEMBL723832 0.85 DRD2 (0.74) TAAR1DRD2DRD1ENPP2CHRM2
SCHEMBL3292837 0.85 DRD2 (0.74) TAAR1DRD2DRD1ENPP2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4378532-B1 COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES MAYO FOUND MEDICAL EDUCATION & RES (US) 2025-11-12 EP claimed
US-20250179086-A1 COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2025-06-05 US claimed
CN-119041239-B Preparation process of thermosensitive coating and thermosensitive paper 江苏金大包装材料科技有限公司 2025-04-25 CN claimed
CN-119331550-A Low-dielectric chip mounting adhesive film composition and adhesive film 北京序轮科技有限公司 2025-01-21 CN claimed
CN-119041239-A Preparation process of thermosensitive coating and thermosensitive paper 江苏金大包装材料科技有限公司 2024-11-29 CN claimed
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-10-31 US claimed
US-20240252463-A1 METHODS OF TREATING FIBROTIC PATHOLOGIES MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2024-08-01 US claimed
EP-4392037-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS Boyce Thompson Institute for Plant Research Inc. (US) 2024-07-03 EP claimed
EP-3745862-B1 D1 DOPAMINE RECEPTOR AGONISTS FOR TREATING FIBROTIC PATHOLOGIES MAYO FOUND MEDICAL EDUCATION & RES (US) 2024-06-26 EP claimed
EP-4378532-A2 COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES Mayo Foundation for Medical Education and Research (US) 2024-06-05 EP claimed
EP-1438053-A1 PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2004-07-21 EP claimed
US-20030171359-A1 Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-09-11 US claimed
WO-2003032997-A1 PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-04-24 WO claimed
US-6346402-B1 ACTS ON OPTICALLY ACTIVE (S)-ALPHA-PHENETHYLAMINE AND PYRUVIC ACID TO FORM ACETOPHENONE AND ALANINE; FOR PRODUCING CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS KANEKA CORPORATION (JP) 2002-02-12 US claimed
EP-1045025-A1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE KANEKA CORPORATION (JP) 2000-10-18 EP claimed
CN-1150178-A Peroxidase or hydrogen peroxide testing method and testing reagent JEOL LTD (JP) 1997-05-21 CN claimed
WO-1996019433-A1 PROCESS FOR PREPARING ACETOXYSTYRENE HOECHST CELANESE CORPORATION (US) 1996-06-27 WO claimed
EP-0517345-B1 Intermediates of the mureidomycin group, their preparation, and their use SANKYO CO (JP) 1995-07-19 EP claimed
EP-0517345-A1 Intermediates of the mureidomycin group, their preparation, and their use SANKYO COMPANY LIMITED (JP) 1992-12-09 EP claimed
US-4242355-A Novel 3-(aminoethyl)-phenols ROUSSEL UCLAF (FR) 1980-12-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179086-A1 COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES MMP1, MMP8, COL2A1 TAAR1 3452/4885DRD2 4882/4885DRD1 4883/4885
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS MAG, PMP22, B3GAT3 TAAR1 4682/4885DRD2 4814/4885DRD1 4874/4885
US-20240252463-A1 METHODS OF TREATING FIBROTIC PATHOLOGIES MMP1, MMP8, COL2A1 TAAR1 3718/4885DRD2 4879/4885DRD1 4882/4885
US-20030171359-A1 Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases COL1A1, MKI67, INSR TAAR1 498/4885DRD2 4752/4885DRD1 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.