Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433138 | 0.84 | BACE1 (0.39) | BACE1NQO1TDP1CYP3A4MEN1 | |
| SCHEMBL766082 | 0.84 | BACE1 (0.39) | BACE1NQO1TDP1CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL10383986 | 0.82 | CA12 (0.37) | BACE1NQO1TDP1CYP3A4MEN1 | |
| SCHEMBL28856744 | 0.80 | HSD17B10 (0.50) | BACE1NQO1TDP1CYP3A4HPGD | |
| SCHEMBL27434588 | 0.80 | TAAR1 (0.44) | BACE1NQO1TDP1CYP3A4MEN1 | |
| SCHEMBL10285567 | 0.80 | TDP1 (0.39) | BACE1NQO1TDP1CYP3A4MEN1 | |
| SCHEMBL1286281 | 0.80 | CYP3A4 (0.46) | TDP1CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL3126597 | 0.79 | ALOX15 (0.48) | TDP1CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL11798878 | 0.79 | CASP1 (0.43) | TDP1CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL1554736 | 0.78 | MEN1 (0.41) | BACE1TDP1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584093-A | Fluororubber for valves and preparation method thereof | 安徽道格思新材料有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-109354809-B | high-Shore-hardness fluororubber composition | 江苏奥纳森弹性体技术研究院有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-109851958-B | High-hardness fluororubber and preparation method thereof | 成都菁尚科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-109851958-A | A kind of high rigidity fluorubber and preparation method thereof | 成都菁尚科技有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109467855-A | A kind of fluorubber of high temperature and pressure contracting ratio | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109401144-A | A kind of fluoro-rubber composite of high temperature and pressure contracting ratio and its application | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109354809-A | A kind of fluoro-rubber composite of high Shao Er hardness | 江苏奥纳森弹性体技术研究院有限公司 | 2019-02-19 | — | — | CN | claimed |
| EP-2337809-B2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2023-11-29 | — | — | EP | disclosed |
| CN-111057050-B | Monomer of bio-based benzoxazine resin, benzoxazine resin and preparation method thereof | 浙江大学宁波理工学院 | 2023-03-03 | — | — | CN | disclosed |
| CN-115584093-A | Fluororubber for valves and preparation method thereof | 安徽道格思新材料有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-113784943-A | Oxygen-containing aminophenol compound and method for preventing polymerization of monomer | 埃科莱布美国股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-109354809-B | high-Shore-hardness fluororubber composition | 江苏奥纳森弹性体技术研究院有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-109851958-B | High-hardness fluororubber and preparation method thereof | 成都菁尚科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| WO-2012058248-A2 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-1866357-B1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO KK (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-8044235-B2 | (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof | SHOWA DENKO K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | SHOWA DENKO K.K. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-5350424-A | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0593038-A1 | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | PRMT5, ACR, PRMT1 | BACE1 4061/4885NQO1 917/4885TDP1 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.