Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326781 | 0.81 | SLC6A9 (0.43) | SLC6A9NPC1RAB9ASCN9AAPP | |
| SCHEMBL6332087 | 0.81 | CDK1 (0.50) | SLC6A9CDK1HPGDKDM4EALDH1A1 | |
| SCHEMBL6321686 | 0.77 | CDK1 (0.44) | SLC6A9NPC1RAB9ACDK1HPGD | |
| SCHEMBL7126958 | 0.77 | MET (0.46) | SLC6A9NPC1RAB9ASCN9AAPP | |
| SCHEMBL6326969 | 0.76 | CDK8 (0.46) | NPC1RAB9ACDK1HPGDALDH1A1 | |
| SCHEMBL6325015 | 0.75 | PDCD1 (0.40) | PPIA | |
| SCHEMBL6321536 | 0.75 | MRGPRX4 (0.38) | PPIAHTTLMNA | |
| SCHEMBL6554549 | 0.74 | SLC6A9 (0.46) | SLC6A9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6554810 | 0.73 | SLC6A9 (0.45) | SLC6A9NPC1RAB9A | |
| SCHEMBL2995355 | 0.72 | F10 (0.43) | HPGDALDH1A1HTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562947-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2005-08-17 | — | — | EP | claimed |
| WO-2004043962-A1 | 4-AMINO-5-PHENYL-7-CYCLOHEXYL-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2004-05-27 | — | — | WO | claimed |
| US-10435225-B2 | Heat sealable food packing films, methods for the production thereof, and food packages comprising heat sealable food packaging films | ADVANSIX RESINS & CHEMICALS LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-20170029196-A1 | HEAT SEALABLE FOOD PACKING FILMS, METHODS FOR THE PRODUCTION THEREOF, AND FOOD PACKAGES COMPRISING HEAT SEALABLE FOOD PACKAGING FILMS | ADVANSIX RESINS & CHEMICALS LLC | 2017-02-02 | — | — | US | disclosed |
| US-6942908-B2 | Antifog/barrier laminate for use in meat packaging | HONEYWELL INTERNATIONAL INC. (US) | 2005-09-13 | — | — | US | disclosed |
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| US-20050101212-A1 | Thin film lamination delamination process to create very thin film on fabric | HONEYWELL INTERNATIONAL INC. | 2005-05-12 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | SLC6A9 3958/4885NPC1 1892/4885RAB9A 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.