Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 15/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321533 | 0.82 | MRGPRX4 (0.37) | PDCD1CD274MRGPRX4PPIAPTGER1 | |
| SCHEMBL6321536 | 0.79 | MRGPRX4 (0.38) | PDCD1CD274MRGPRX4PPIAPTGER1 | |
| SCHEMBL6324682 | 0.75 | SLC6A9 (0.43) | PPIA | |
| SCHEMBL6332087 | 0.71 | CDK1 (0.50) | MRGPRX4 | |
| SCHEMBL6554457 | 0.69 | CTSL (0.39) | PDCD1CD274MRGPRX4PTGER1 | |
| SCHEMBL6321686 | 0.67 | CDK1 (0.44) | MRGPRX4 | |
| SCHEMBL6326969 | 0.66 | CDK8 (0.46) | — | |
| SCHEMBL8167961 | 0.65 | MRGPRX4 (0.55) | PDCD1CD274MRGPRX4 | |
| SCHEMBL6554509 | 0.64 | EPHX2 (0.46) | MRGPRX4 | |
| SCHEMBL1978691 | 0.64 | MAOB (0.55) | PDCD1CD274MRGPRX4PPIAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | PDCD1 2405/4885CD274 3131/4885MRGPRX4 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.