SCHEMBL632498

SCHEMBL632498

O=C1CCCC(=O)C2C(=O)[N]C(=O)C12

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225809 0.69 KMT2A (0.50) CA1CA2CA4KMT2A
SCHEMBL7825990 0.64 CA1 (0.32) CA1CA2CA4KMT2A
SCHEMBL609340 0.63 ALDH1A1 (0.33) CA1CA2CA4KMT2A
SCHEMBL5336897 0.63 CA1 (0.40) CA1CA2CA4KMT2A
SCHEMBL171969 0.61
SCHEMBL7549489 0.61
SCHEMBL11782120 0.61
SCHEMBL10882169 0.61
SCHEMBL280398 0.61
SCHEMBL28564764 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2093245-B1 Biocompatible polymer device ANGIODEVICE INTERNAT GMBH (CH) 2012-02-22 EP disclosed
EP-2093245-A2 Biocompatible polymer device AngioDevice International GmbH (CH) 2009-08-26 EP disclosed
EP-1218437-B1 COMPOSITIONS THAT FORM INTERPENETRATING POLYMER NETWORKS FOR USE AS HIGH STRENGTH MEDICAL SEALANTS ANGIODEVICE INTERNAT GMBH (CH) 2009-06-17 EP disclosed
US-6495127-B1 INTERPENETRATING POLYMER NETWORKS COHESION TECHNOLOGIES, INC. 2002-12-17 US disclosed
EP-1218437-A1 COMPOSITIONS THAT FORM INTERPENETRATING POLYMER NETWORKS FOR USE AS HIGH STRENGTH MEDICAL SEALANTS Cohesion Technologies, Inc. (US) 2002-07-03 EP disclosed
WO-2001016210-A1 COMPOSITIONS THAT FORM INTERPENETRATING POLYMER NETWORKS FOR USE AS HIGH STRENGTH MEDICAL SEALANTS COHESION TECHNOLOGIES, INC. (US) 2001-03-08 WO disclosed