SCHEMBL609340

SCHEMBL609340

O=C1CCCC(=O)C2C(=O)[N+](O)C(=O)C12

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225809 0.66 KMT2A (0.50) ALDH1A1MAPTCA1CA2CA4
SCHEMBL7549489 0.64
SCHEMBL632498 0.63 CA1 (0.33) CA1CA2CA4KMT2A
SCHEMBL28122971 0.61 ALDH1A1 (0.38) ALDH1A1MAPTL3MBTL1CA1CA2
SCHEMBL7825990 0.61 CA1 (0.32) CA1CA2CA4KMT2A
SCHEMBL12475098 0.60 L3MBTL1 (0.41) ALDH1A1MAPTL3MBTL1CA1CA2
SCHEMBL5336897 0.60 CA1 (0.40) ALDH1A1MAPTCA1CA2CA4
SCHEMBL382537 0.59 HPD (0.36) ALDH1A1MAPTL3MBTL1CA1CA2
SCHEMBL170644 0.58 CA1 (0.39) ALDH1A1MAPTL3MBTL1CA1CA2
SCHEMBL26828454 0.58 CA1 (0.50) ALDH1A1MAPTCA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160228601-A1 BIOCOMPATIBLE CROSSLINKED HYDROGELS, DRUG-LOADED HYDROGELS AND METHODS OF USING THE SAME SURGICAL SPECIALTIES CORPORATION LIMITED (GB) 2016-08-11 US disclosed
US-9353218-B2 Kit for multifunctional compounds forming crosslinked biomaterials ANGIOTECH PHARMACEUTICALS, INC. 2016-05-31 US disclosed
US-9326934-B2 Drug delivery from rapid gelling polymer composition ANGIOTECH INTERNATIONAL AG 2016-05-03 US disclosed
US-9125814-B2 Biocompatible crosslinked hydrogels, drug-loaded hydrogels and methods of using the same ANGIOTECH PHARMACEUTICALS, INC. (CA) 2015-09-08 US disclosed
EP-2181704-B1 Drug delivery from rapid gelling polymer composition ANGIOTECH INT AG (CH) 2015-05-06 EP disclosed
US-8617584-B2 Adhesive tissue repair patch and collagen sheets ANGIODEVICE INTERNATIONAL GMBH (CH) 2013-12-31 US disclosed
US-20130289235-A1 MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE ANGIOTECH PHARMACEUTICALS, INC. (CA) 2013-10-31 US disclosed
US-8486437-B2 Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use ANGIOTECH PHARMACEUTICALS (US), INC. (US) 2013-07-16 US disclosed
US-8481073-B2 Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use ANGIODEVICE INTERNATIONAL GMBH (CH) 2013-07-09 US disclosed
US-8460708-B2 Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use ANGIODEVICE INTERNATIONAL GMBH (CH) 2013-06-11 US disclosed
WO-2002102864-A1 COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE COHESION TECHNOLOGIES, INC. (US) 2002-12-27 WO disclosed
US-6495127-B1 INTERPENETRATING POLYMER NETWORKS COHESION TECHNOLOGIES, INC. 2002-12-17 US disclosed
US-6482179-B1 Apparatuses, methods and compositions for closing tissue puncture openings COHESION TECHNOLOGIES, INC. 2002-11-19 US disclosed
US-20020165337-A1 Rapid-gelling biocompatible polymer composition and associated methods of preparation and use ANGIODEVICE INTERNATIONAL GMBH (CH) 2002-11-07 US disclosed
US-6458889-B1 CROSSLINKING NUCLEOPHILIC AND ELECTROPHILIC MATERIAL; BONDING STRENGTH COHESION TECHNOLOGIES, INC. 2002-10-01 US disclosed
EP-1218437-A1 COMPOSITIONS THAT FORM INTERPENETRATING POLYMER NETWORKS FOR USE AS HIGH STRENGTH MEDICAL SEALANTS Cohesion Technologies, Inc. (US) 2002-07-03 EP disclosed
US-20020042473-A1 Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use ANGIODEVICE INTERNATIONAL GMBH (CH) 2002-04-11 US disclosed
US-20010055615-A1 SULFHYDRYL GROUP REACTIVE WITH GROUPS AND POLYOXYALKYLENE OXIDE ANGIODEVICE INTERNATIONAL GMBH (CH) 2001-12-27 US disclosed
US-6312725-B1 SULFHYDRYL GROUP REACTIVE WITH GROUPS AND POLYOXYALKYLENE OXIDE COHESION TECHNOLOGIES, INC. 2001-11-06 US disclosed
WO-2001016210-A1 COMPOSITIONS THAT FORM INTERPENETRATING POLYMER NETWORKS FOR USE AS HIGH STRENGTH MEDICAL SEALANTS COHESION TECHNOLOGIES, INC. (US) 2001-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228601-A1 BIOCOMPATIBLE CROSSLINKED HYDROGELS, DRUG-LOADED HYDROGELS AND METHODS OF USING THE SAME PTGES, PTGS1, HPGDS ALDH1A1 168/4885MAPT 4006/4885L3MBTL1 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.