SCHEMBL6330192

SCHEMBL6330192

CCCOC(=O)OC1CCCC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.33
EPHX1 P07099 1/20 0.32
SCN9A Q15858 3/20 0.32
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
AKT1 P31749 1/20 0.30
AKT2 P31751 1/20 0.30
AKT3 Q9Y243 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6337110 0.88 ALDH1A1 (0.38) NAAAEPHX1SCN9ACYP2C19
SCHEMBL6325221 0.87 NAAA (0.33) NAAAEPHX1SCN9APPM1BPTPN1
SCHEMBL6332696 0.84 NAAA (0.37) NAAAEPHX1SCN9APPM1BPTPN1
SCHEMBL12987689 0.83 SCN9A (0.34) EPHX1SCN9ACYP2C19
SCHEMBL8378630 0.80 NAAA (0.44) NAAAEPHX1PPM1BPTPN1PPP1CC
SCHEMBL450994 0.80 NAAA (0.49) NAAAEPHX1PPM1BPTPN1PPP1CC
SCHEMBL6335395 0.79 SCN9A (0.37) EPHX1SCN9ACYP2C19
SCHEMBL8631017 0.79 NAAA (0.50) NAAAEPHX1PPM1BPTPN1PPP1CC
SCHEMBL11590190 0.79 NAAA (0.50) NAAAEPHX1PPM1BPTPN1PPP1CC
SCHEMBL11589171 0.79 NAAA (0.50) NAAAEPHX1PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919477-B2 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-07-19 US disclosed
US-6774260-B2 ALKYL 1-(3,3-DIMETHYLCYCLOHEXYL) ETHYL MALONATE DERIVATIVES; SOAPS, COSMETICS, PERFUMES, CLEANING COMPOUNDS, DETERGENTS; MUSKY ODOR INTERNATIONAL FLAVORS & FRAGRANCES INC. 2004-08-10 US disclosed
EP-1398366-A1 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2004-03-17 EP disclosed