SCHEMBL6325376

SCHEMBL6325376

CCCOC(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.60
CA9 Q16790 2/20 0.60
TP53 P04637 1/20 0.60
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA4 P22748 1/20 0.60
CA6 P23280 1/20 0.60
CA5A P35218 1/20 0.60
CA7 P43166 1/20 0.60
CA13 Q8N1Q1 1/20 0.60
CA14 Q9ULX7 1/20 0.60
LMNA P02545 4/20 0.59
KMT2A Q03164 5/20 0.57
GAA P10253 1/20 0.57
RAB9A P51151 2/20 0.57
PPARG P37231 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
NR2E3 Q9Y5X4 1/20 0.57
NCOR2 Q9Y618 1/20 0.57
MEN1 O00255 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395597 0.93 HPGD (0.58) CA2CA9TP53CA12CA1
SCHEMBL1883464 0.92 CA2 (0.61) CA2CA9TP53CA12CA1
SCHEMBL6723821 0.92 CA2 (0.61) CA2CA9TP53CA12CA1
SCHEMBL5184903 0.91 KMT2A (0.69) CA2CA9TP53CA12CA1
SCHEMBL6720805 0.91 CA2 (0.60) CA2CA9TP53CA12CA1
SCHEMBL6720823 0.89 ALDH1A1 (0.53) CA2CA9CA12CA1LMNA
SCHEMBL6725193 0.89 ALDH1A1 (0.59) CA9CA12LMNAKMT2ARAB9A
SCHEMBL6332397 0.88 CA2 (0.57) CA2CA9TP53CA12CA1
SCHEMBL20981707 0.87 NHERF1 (0.67) CA2CA9TP53CA12CA1
SCHEMBL6321973 0.86 LMNA (0.57) CA2CA9TP53CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed