Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 5/20 | 0.43 |
| ▸ | FZD7 | O75084 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329116 | 0.87 | MAPT (0.51) | LMNAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL6326257 | 0.87 | MAPT (0.51) | LMNAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL6335374 | 0.85 | STAT3 (0.54) | LMNAHTTMAPTRAB9ANPC1 | |
| SCHEMBL6329876 | 0.84 | MAPT (0.44) | LMNAHTTPPARAMAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL6337264 | 0.83 | DGAT1 (0.51) | LMNAMAPTRAB9ANPC1MEN1 | |
| SCHEMBL6334826 | 0.79 | MAPT (0.49) | MAPTTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6330411 | 0.79 | PPARA (0.69) | PPARAMAPTMEN1KMT2APPARG | |
| SCHEMBL6335252 | 0.78 | PPARA (0.49) | LMNAPPARAMAPTNPC1MEN1 | |
| SCHEMBL6334499 | 0.77 | PPARA (0.47) | LMNAPPARAMAPTNPC1MEN1 | |
| SCHEMBL6330513 | 0.77 | L3MBTL1 (0.55) | LMNAHTTMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014805-A1 | Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014805-A1 | Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity | GPR119, EGLN3, PC | LMNA 2130/4885HTT 40/4885PPARA 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.