SCHEMBL632593

SCHEMBL632593

NCc1ccccc1CCO

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.48
PNMT P11086 3/20 0.46
TDP1 Q9NUW8 1/20 0.44
TAAR1 Q96RJ0 6/20 0.43
HTR2A P28223 1/20 0.40
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31203 0.87 TDP1 (0.55) DPP4TDP1TAAR1HTR2A
SCHEMBL29534868 0.87 TDP1 (0.55) DPP4TDP1TAAR1HTR2A
SCHEMBL5629736 0.86 DPP4 (0.45) DPP4PNMTTDP1TAAR1HTR2A
SCHEMBL6875195 0.85 TAAR1 (0.60) TDP1TAAR1HTR2ASMN1; SMN2LOXL2
SCHEMBL28807672 0.82 DPP4 (0.35) DPP4PNMTTDP1TAAR1
SCHEMBL15247 0.81 PNMT (0.63) DPP4PNMTTAAR1KDM4ESMN1; SMN2
SCHEMBL29405036 0.81 PNMT (0.63) DPP4PNMTTAAR1KDM4ESMN1; SMN2
Propanol SCHEMBL29016029 0.80 DPP4 (0.48) DPP4PNMTTAAR1KDM4ESMN1; SMN2
SCHEMBL2553273 0.79 DPP4 (0.52) DPP4PNMTTAAR1KDM4ESMN1; SMN2
SCHEMBL3051426 0.79 TAAR1 (0.61) DPP4PNMTTAAR1HTR2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
CN-106459831-A Improvements in or relating to organic compounds 奇华顿股份有限公司 2017-02-22 CN claimed
CN-105308162-A Compounds for a controlled release of active molecules FIRMENICH & CIE 2016-02-03 CN claimed
CN-103641769-B The preparation method of isoindoline hydrochloride ASTATECH (CHENGDU) PHARM. CO., LTD. (CN) 2015-11-04 CN claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
CN-103641769-A Preparation method of isoindoline hydrochloride ASTATECH CHENGDU PHARMACEUTICAL CO LTD 2014-03-19 CN claimed
CN-101193950-A Fragrance alcohol-releasing polysiloxane DEGUSSA (DE) 2008-06-04 CN claimed
CN-100390261-C Compositions comprising photo-labile perfume delivery systems PROCTER & GAMBLE (US) 2008-05-28 CN claimed
CN-1553948-A Compositions comprising photo-labile perfume delivery systems 2004-12-08 CN claimed
CN-1254552-A Ceratin-fibre composition for oxidation dying and method for dying with solid composition OREAL (FR) 2000-05-31 CN claimed
US-20230278959-A1 Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization MISSISSIPPI STATE UNIVERSITY 2023-09-07 US disclosed
EP-3941424-A1 HAIR COLORANT COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2022-01-26 EP disclosed
US-10604509-B2 Nrf2 regulators GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2020-03-31 US disclosed
CN-109310636-A The production method of dosage form OMYA国际股份公司 2019-02-05 CN disclosed
CN-109310637-A The production method of dosage form OMYA国际股份公司 2019-02-05 CN disclosed
CN-1233284-A Fragrance delivery system for liquid detergent compositions PROCTER & GAMBLE (US) 1999-10-27 CN disclosed
CN-1210858-A Optically active bisoxazoline compounds, process for their preparation and their use SUMITOMO CHEMICAL CO (JP) 1999-03-17 CN disclosed
CN-1202163-A Benzothiazolone derivatives ASTRA PHARMA PROD (GB) 1998-12-16 CN disclosed
EP-0087676-B1 PROCESS FOR THE PREPARATION OF O-ACYLAMINOMETHYLBENZYL HALOGENIDES BASF Aktiengesellschaft (DE) 1987-12-16 EP disclosed
EP-0087676-A1 Process for the preparation of o-acylaminomethylbenzyl halogenides BASF Aktiengesellschaft (DE) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278959-A1 Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization INMT, IDO2, WEE2 DPP4 4110/4885PNMT 277/4885TDP1 2890/4885
US-10604509-B2 Nrf2 regulators NFE2L2, KEAP1, NQO1 DPP4 3682/4885PNMT 1835/4885TDP1 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.