Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813449 | 0.85 | KDM4E (0.41) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL6260027 | 0.82 | KDM4E (0.52) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL1641735 | 0.78 | L3MBTL1 (0.42) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL6323487 | 0.76 | CDK2 (0.50) | MAPK1CDK2NPC1RAB9AMAPT | |
| SCHEMBL5817322 | 0.74 | MAPK14 (0.52) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL5813444 | 0.74 | KDM4E (0.42) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL5818427 | 0.73 | KDM4E (0.42) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL5818860 | 0.73 | LMNA (0.44) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL23602753 | 0.73 | LMNA (0.51) | KDM4EL3MBTL1NPSR1MAPK1LMNA | |
| SCHEMBL5815370 | 0.72 | POLB (0.40) | KDM4EL3MBTL1NPSR1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038059-A1 | Thiazolyl substituted aminopyrimidines as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038059-A1 | Thiazolyl substituted aminopyrimidines as plant protection agents | RARS2, CYP4X1, QDPR | KDM4E 1004/4885L3MBTL1 1848/4885NPSR1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.