Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326438 | 1.00 | CHRM3 (0.41) | CHRM3ROCK2PRMT5WDR77LOXL2 | |
| SCHEMBL6130341 | 0.89 | CHRM3 (0.42) | CHRM3ROCK2PRMT5WDR77LOXL2 | |
| Hydrochloric Acid SCHEMBL6316344 | 0.88 | CHRM3 (0.42) | CHRM3ROCK2PRMT5WDR77LOXL2 | |
| SCHEMBL6319178 | 0.83 | CHRM3 (0.42) | CHRM3ROCK2PRMT5WDR77KDM1A | |
| SCHEMBL6316361 | 0.83 | KDM4E (0.47) | KDM1AST14 | |
| SCHEMBL6316359 | 0.83 | KDM4E (0.47) | KDM1AST14 | |
| SCHEMBL6130337 | 0.75 | F10 (0.51) | ST14 | |
| SCHEMBL7063308 | 0.75 | CHRM3 (0.40) | CHRM3ROCK2LOXL2ST14 | |
| SCHEMBL6817718 | 0.73 | F10 (0.46) | ROCK2KDM1A | |
| SCHEMBL6832947 | 0.72 | CHRM3 (0.44) | CHRM3ROCK2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | TEIJIN LIMITED (JP) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | AOC2, TALDO1, AOC1 | CHRM3 673/4885ROCK2 3243/4885PRMT5 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.