Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832947 | 0.89 | CHRM3 (0.44) | CHRM3ROCK2PRMT5WDR77VNN1 | |
| SCHEMBL6751721 | 0.86 | PLAU (0.41) | CHRM3ROCK2PLAUMRGPRX4MCHR1 | |
| SCHEMBL6130341 | 0.85 | CHRM3 (0.42) | CHRM3ROCK2PRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL6316344 | 0.84 | CHRM3 (0.42) | CHRM3ROCK2PRMT5WDR77 | |
| SCHEMBL6318034 | 0.83 | KDM4E (0.46) | — | |
| SCHEMBL6326438 | 0.83 | CHRM3 (0.41) | CHRM3ROCK2PRMT5WDR77KDM1A | |
| SCHEMBL6326432 | 0.83 | CHRM3 (0.41) | CHRM3ROCK2PRMT5WDR77KDM1A | |
| SCHEMBL7039054 | 0.83 | MGLL (0.55) | TSHR | |
| SCHEMBL7041177 | 0.81 | HRH2 (0.44) | VNN1MCHR1 | |
| SCHEMBL7039071 | 0.81 | HRH2 (0.44) | VNN1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | TEIJIN LIMITED (JP) | 2005-05-12 | — | — | US | disclosed |
| CN-1489575-A | Benzamidine derivatives and process for producing same | ������������ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| US-20030203935-A1 | Cyanobiphenyl derivatives | TEIJIN LIMITED | 2003-10-30 | — | — | US | disclosed |
| EP-1357108-A1 | BENZAMIDINE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6538137-B1 | Blood-coagulation factor X inhibitors | TEIJIN LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1179527-A1 | CYANOBIPHENYL DERIVATIVES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | AOC2, TALDO1, AOC1 | CHRM3 673/4885ROCK2 3243/4885PLAU 2846/4885 |
| US-20030203935-A1 | Cyanobiphenyl derivatives | F9, F12, F11 | CHRM3 3393/4885ROCK2 2136/4885PLAU 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.