Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204121 | 1.00 | LMNA (0.64) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL6327817 | 0.91 | LMNA (0.73) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL6325847 | 0.91 | MAPT (0.64) | LMNAL3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL6221813 | 0.85 | MAPT (0.52) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL3868073 | 0.85 | MAPT (0.63) | LMNAL3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL11847871 | 0.83 | LMNA (0.64) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL6321338 | 0.83 | MAPT (0.64) | LMNAL3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL11488970 | 0.83 | MAPT (0.64) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL6328277 | 0.83 | MAPT (0.64) | LMNAL3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL6319805 | 0.83 | MAPT (0.68) | LMNAL3MBTL1MAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| US-5041458-A | Fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-20 | — | — | US | disclosed |