Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321338 | 1.00 | MAPT (0.64) | MAPTALDH1A1HTTHSD17B10HPGD | |
| SCHEMBL21100591 | 0.91 | MAPT (0.73) | MAPTALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL6325847 | 0.91 | MAPT (0.64) | MAPTL3MBTL1KDM4ELMNANPC1 | |
| SCHEMBL3866097 | 0.87 | MAPT (0.57) | MAPTALDH1A1HTTHSD17B10L3MBTL1 | |
| SCHEMBL6318934 | 0.87 | MAPT (0.78) | MAPTL3MBTL1KDM4ELMNAKCNH2 | |
| SCHEMBL6202777 | 0.87 | MAPT (0.64) | MAPTALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL6319805 | 0.87 | MAPT (0.68) | MAPTALDH1A1HTTHSD17B10L3MBTL1 | |
| SCHEMBL6326124 | 0.86 | MAPT (0.56) | MAPTALDH1A1HTTHSD17B10L3MBTL1 | |
| SCHEMBL7168347 | 0.85 | MAPT (0.71) | MAPTALDH1A1HTTHSD17B10MEN1 | |
| SCHEMBL31357494 | 0.85 | MAPT (0.70) | MAPTALDH1A1HTTHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375641-A | C3-phenoxy substituted quinoline compound and synthetic method and application thereof | 杭州师范大学 | 2023-07-04 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |