SCHEMBL6325847

SCHEMBL6325847

O=C(COc1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.64
LMNA P02545 2/20 0.64
KDM4E B2RXH2 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NPC1 O15118 1/20 0.56
GSK3B P49841 2/20 0.55
NR4A2 P43354 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3868073 0.93 MAPT (0.63) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6202777 0.91 MAPT (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6318934 0.91 MAPT (0.78) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6319805 0.91 MAPT (0.68) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6321338 0.91 MAPT (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6326562 0.91 LMNA (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6328277 0.91 MAPT (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6204121 0.91 LMNA (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL6205126 0.91 L3MBTL1 (0.60) MAPTLMNAKDM4EL3MBTL1RAB9A
SCHEMBL658106 0.91 MAPT (0.64) MAPTLMNAKDM4EL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903453-A Recycling method of 2-chloro-4- (4-chlorophenoxy) acetophenone raffinate 浙江宇龙生物科技股份有限公司 2023-10-20 CN claimed
CN-120682090-A Recycling treatment method for 2-chloro-4- (4-chlorophenoxy) acetophenone raffinate 甘肃贝达生物科技有限公司 2025-09-23 CN disclosed
CN-116903453-A Recycling method of 2-chloro-4- (4-chlorophenoxy) acetophenone raffinate 浙江宇龙生物科技股份有限公司 2023-10-20 CN disclosed
CN-116903453-A Recycling method of 2-chloro-4- (4-chlorophenoxy) acetophenone raffinate 浙江宇龙生物科技股份有限公司 2023-10-20 CN disclosed
US-20050272036-A1 Ketones ASTRAZENECA AB (SE) 2005-12-08 US disclosed
CN-1681763-A Chemical compounds ASTRAZENECA AB (SE) 2005-10-12 CN disclosed
US-20050107457-A1 Indazole derivatives as JNK inhibitors and compositions and methods related thereto SINGNAL PHARMACEUTICALS, INC. 2005-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107457-A1 Indazole derivatives as JNK inhibitors and compositions and methods related thereto MAP3K7, MAP3K1, MAP3K8 MAPT 978/4885LMNA 2859/4885KDM4E 3349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.