SCHEMBL30104899

SCHEMBL30104899

O=C1OC(Oc2ccccc2)C(SCc2ccccc2)=C1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.38
DAO P14920 4/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34
ELANE P08246 2/20 0.33
MAOB P27338 2/20 0.33
ALDH1A1 P00352 2/20 0.33
S100A4 P26447 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
CTSB P07858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30104898 0.84 CCKBR (0.41) CCKBRDAOLMNAMAPTGAA
SCHEMBL30104867 0.82 MAPK1 (0.47) CCKBRDAOLMNAMAPTGAA
SCHEMBL6326740 0.74 NSD2 (0.37) CCKBRLMNAMAPTGAAALDH1A1
SCHEMBL30104874 0.70 CCKBR (0.59) CCKBRLMNAMAPTALDH1A1CTSB
SCHEMBL30104902 0.68 S100A4 (0.37) DAOLMNAMAPTPKMELANE
SCHEMBL30104857 0.67 CTSV (0.33) GAACTSB
SCHEMBL3625933 0.67 EP300 (0.46) GAAELANEALDH1A1POLB
SCHEMBL30104893 0.67 CCKBR (0.41) CCKBRDAOLMNAELANEMAOB
SCHEMBL30104840 0.66 NR2E3 (0.37) CCKBRDAOLMNAMAPTELANE
SCHEMBL30104872 0.65 POLB (0.38) CCKBRDAOLMNAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583927-B Thioether compound, and preparation method and application thereof 华南师范大学 2024-07-12 CN disclosed
CN-115583927-A Thioether compound and preparation method and application thereof 华南师范大学 2023-01-10 CN disclosed