Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6328364 | 0.93 | DGAT1 (0.44) | NPC1RAB9ATP53MAPK1DGAT1 | |
| SCHEMBL6326588 | 0.92 | DGAT1 (0.49) | NPC1RAB9ATP53MAPK1DGAT1 | |
| Trifluoroacetic Acid SCHEMBL6332856 | 0.92 | DGAT1 (0.43) | NPC1RAB9ADGAT1MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6325794 | 0.91 | NPC1 (0.42) | NPC1RAB9ATP53MAPK1PKM | |
| SCHEMBL6327445 | 0.90 | MAPT (0.44) | NPC1RAB9ATP53MAPK1PKM | |
| Trifluoroacetic Acid SCHEMBL6334767 | 0.86 | DGAT1 (0.47) | NPC1RAB9ADGAT1MAPTALDH1A1 | |
| SCHEMBL5726776 | 0.85 | DGAT1 (0.47) | NPC1RAB9ATP53MAPK1DGAT1 | |
| SCHEMBL6335252 | 0.84 | PPARA (0.49) | NPC1TP53MAPK1MAPTALDH1A1 | |
| SCHEMBL6329108 | 0.84 | HIPK4 (0.40) | NPC1RAB9ATP53MAPK1MAPT | |
| SCHEMBL5727205 | 0.84 | DGAT1 (0.46) | NPC1RAB9ATP53MAPK1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014805-A1 | Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014805-A1 | Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity | GPR119, EGLN3, PC | NPC1 315/4885RAB9A 2132/4885TP53 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.