Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 5/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652813 | 0.79 | MAPK14 (0.64) | LMNAALOX15HSD17B10MAPK14MAPK13 | |
| SCHEMBL6652431 | 0.79 | ELANE (0.51) | ELANEALDH1A1STSHTTKMT2A | |
| SCHEMBL4636514 | 0.76 | ALDH1A1 (0.53) | ALOX15HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL322168 | 0.75 | CTSD (0.62) | LMNAALOX15HSD17B10ELANECTSD | |
| SCHEMBL29658169 | 0.75 | CTSD (0.62) | LMNAALOX15HSD17B10ELANECTSD | |
| SCHEMBL10713056 | 0.75 | RORC (0.56) | LMNARORBRORCALDH1A1MEN1 | |
| SCHEMBL596796 | 0.74 | ALDH1A1 (0.39) | ALOX15HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL27789892 | 0.74 | CTSD (0.60) | LMNAALOX15HSD17B10ELANECTSD | |
| SCHEMBL6656065 | 0.73 | STS (0.64) | LMNAALOX15HSD17B10MAPK14CTSD | |
| SCHEMBL3818697 | 0.73 | KDM4E (0.59) | LMNAALOX15HSD17B10MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960553-B2 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20030186810-A1 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. | 2003-10-02 | — | — | US | disclosed |