Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | AGER | Q15109 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SCD | O00767 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329789 | 0.85 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL16378731 | 0.82 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL6328478 | 0.82 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL6330529 | 0.80 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL4287864 | 0.79 | ADORA2A (0.63) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL3223685 | 0.79 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL6327447 | 0.78 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL6328469 | 0.78 | GLA (0.45) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8298569 | 0.77 | AGER (0.73) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 | |
| SCHEMBL4286191 | 0.77 | ADORA2A (1.00) | NPC1RAB9ASMN1; SMN2ADORA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949654-B2 | N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2005-09-27 | — | — | US | claimed |
| US-6949654-B2 | N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2005-09-27 | — | — | US | disclosed |
| US-20030225087-A1 | N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2003-12-04 | — | — | US | disclosed |
| WO-2003010153-A1 | N-ALKYL-N-PHENYLHYDROXYLAMINE COMPOUNDS CONTAINING METAL CHELATING GROUPS, THEIR PREPARATION AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225087-A1 | N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses | SOD1, LPO, BAD | NPC1 322/4885RAB9A 539/4885SMN1; SMN2 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.