Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.74 |
| ▸ | MEN1 | O00255 | 10/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | TP53 | P04637 | 9/20 | 0.74 |
| ▸ | HPGD | P15428 | 8/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | RAF1 | P04049 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357670 | 1.00 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9420982 | 0.85 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL861728 | 0.85 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL861729 | 0.85 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL12162614 | 0.84 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL1566918 | 0.84 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL1566916 | 0.84 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL16296742 | 0.84 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL16296740 | 0.84 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL16296767 | 0.83 | MAOA (0.82) | MAPTMEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6941051-B2 | Method for producing non-linear optical organic crystal film | REVEO, INC. (US) | 2005-09-06 | — | — | US | claimed |
| US-20040033038-A1 | Method for producing non-linear optical organic crystal film | XU JIANJUN (US) | 2004-02-19 | — | — | US | claimed |
| US-6577798-B2 | Method for producing non-linear optical organic crystal film | REVEO, INC. | 2003-06-10 | — | — | US | claimed |
| US-20020041427-A1 | Method for producing non-linear optical organic crystal film | REVEO, INC. | 2002-04-11 | — | — | US | claimed |
| WO-2002008828-A2 | COMPOSITE NONLINEAR OPTICAL FILM, METHOD OF PRODUCING THE SAME AND APPLICATIONS OF THE SAME | REVEO, INC. (US) | 2002-01-31 | — | — | WO | claimed |
| WO-2002006890-A2 | METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM | REVEO, INC. (US) | 2002-01-24 | — | — | WO | claimed |
| US-6303056-B1 | Composite nonlinear optical film, method of producing the same and applications of the same | REVEO, INC. | 2001-10-16 | — | — | US | claimed |
| EP-0420216-B1 | Use of a material as non-linear optical material and non-linear optical device | NIPPON OILS & FATS CO LTD (JP) | 1994-11-30 | — | — | EP | claimed |
| US-5144044-A | 3-(2-thienyl)-1-(4-methylphenyl)propene-3-one | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-09-01 | — | — | US | claimed |
| EP-0420216-A2 | Use of a material as non-linear optical material and non-linear optical device | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | claimed |
| JP-3179329-A | — | — | None | — | — | JP | disclosed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-5144044-A | 3-(2-thienyl)-1-(4-methylphenyl)propene-3-one | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-5144044-A | 3-(2-thienyl)-1-(4-methylphenyl)propene-3-one | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| JP-H03179329-A | NONLINEAR OPTICAL MATERIAL AND NONLINEAR OPTICAL ELEMENT | NIPPON OIL & FATS CO LTD | 1991-08-05 | — | — | JP | disclosed |
| EP-0420216-A2 | Use of a material as non-linear optical material and non-linear optical device | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0420216-A2 | Use of a material as non-linear optical material and non-linear optical device | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | MAPT 2150/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | MAPT 2150/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | MAPT 2150/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | MAPT 2150/4885MEN1 4484/4885KMT2A 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.