SCHEMBL632912

SCHEMBL632912

CC(C)Nc1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.56
ALDH1A1 P00352 5/20 0.54
LMNA P02545 4/20 0.54
TSHR P16473 3/20 0.54
CYP3A4 P08684 2/20 0.54
THRB P10828 2/20 0.54
ALOX15 P16050 2/20 0.54
HSD17B10 Q99714 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALOX12 P18054 1/20 0.54
RECQL P46063 1/20 0.54
ATM Q13315 1/20 0.54
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
KCNH3 Q9ULD8 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9020829 0.97 TDP1 (0.54) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL22967371 0.87 CA2 (0.57) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL39430 0.86 TDP1 (0.72) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL19707721 0.82 MEN1 (0.48) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL6196686 0.80 ADRB2 (0.50) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL22427774 0.80 MEN1 (0.47) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL1006554 0.80 MEN1 (0.52) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL10354265 0.80 MEN1 (0.47) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL13101491 0.79 TDP1 (0.56) TDP1ALDH1A1LMNATSHRCYP3A4
SCHEMBL22967401 0.78 MAOB (0.56) LMNAMEN1KMT2AMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117019072-A Method and device for continuously producing anilofos 德州绿霸精细化工有限公司 2023-11-10 CN claimed
CN-113698430-B Preparation method of herbicide anilofos 潍坊新绿化工有限公司 2022-01-25 CN claimed
CN-113698430-A Preparation method of herbicide anilofos 潍坊新绿化工有限公司 2021-11-26 CN claimed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US claimed
EP-0348737-B1 HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES BAYER AG (DE) 1993-08-04 EP claimed
US-20240425500-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-12-26 US disclosed
CN-118841063-A Construction method and application of autophagy regulatory factor prediction model 华中科技大学 2024-10-25 CN disclosed
CN-118043321-A Imidazo [1,2-a ] pyridine derivatives 先正达农作物保护股份公司 2024-05-14 CN disclosed
CN-117229210-A Decahydroisoquinoline compound and preparation method and application thereof 中国科学院上海药物研究所 2023-12-15 CN disclosed
CN-117202907-A Method for delaying ejaculation in human males 卡纳健康有限公司 2023-12-08 CN disclosed
CN-117019072-A Method and device for continuously producing anilofos 德州绿霸精细化工有限公司 2023-11-10 CN disclosed
CN-117019072-A Method and device for continuously producing anilofos 德州绿霸精细化工有限公司 2023-11-10 CN disclosed
WO-1991000262-A1 METHOD OF PREPARING N-ALKYL-HALOANILINES HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-10 WO disclosed
EP-0355351-A2 Process for the preparation of amines BAYER AG (DE) 1990-02-28 EP disclosed
US-4500341-A PREEMERGENCE, POSTEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-02-19 US disclosed
EP-0014880-B1 PHENOXYCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1982-09-22 EP disclosed
US-4243407-A 2-Acylaminothiazol-4-ylacetamides as post emergent selective herbicides GULF OIL CORPORATION (US) 1981-01-06 US disclosed
US-4232163-A 2-Acylaminothiazol-4-ylacetamides as post emergent selective herbicides GULF OIL CORPORATION (US) 1980-11-04 US disclosed
EP-0014880-A1 Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides BAYER AG (DE) 1980-09-03 EP disclosed
US-4152428-A NEMATOCIDES, MITICIDES AND INSECTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT TDP1 716/4885ALDH1A1 926/4885LMNA 2266/4885
US-20240425500-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES IDO1, CYP1A1, CYP4Z1 TDP1 1165/4885ALDH1A1 399/4885LMNA 3155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.