Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830291 | 0.88 | MELK (0.40) | MELKEGLN1EGFRRXRAGRIN1 | |
| SCHEMBL6330405 | 0.88 | CHRNB2 (0.43) | CHRNB2CHRNA4MELKEGLN1NPC1 | |
| SCHEMBL6339239 | 0.78 | GRM5 (0.39) | MELKRXRAGRIN1GRIN2BMEN1 | |
| SCHEMBL6603575 | 0.77 | CHRNB2 (0.44) | CHRNB2CHRNA4EGLN1NPC1POLB | |
| SCHEMBL6328488 | 0.74 | HTT (0.41) | POLBEGFRRXRAGRIN1GRIN2B | |
| SCHEMBL6332341 | 0.71 | GRM5 (0.42) | EGFR | |
| SCHEMBL2432983 | 0.69 | SMN1; SMN2 (0.47) | RXRAGRIN1GRIN2BALDH1A1LMNA | |
| SCHEMBL13035343 | 0.65 | CYP2C19 (0.61) | CHRNB2CHRNA4FFAR1CYP2C9 | |
| SCHEMBL23375370 | 0.64 | KDM4E (0.55) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9290566 | 0.63 | CHRNB2 (0.54) | CHRNB2CHRNA4POLBFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | DDT, CHRM1, CYP4X1 | CHRNB2 1382/4885CHRNA4 671/4885MELK 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.