Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329779 | 0.88 | CHRNB2 (0.45) | MELKKCNH2EGLN1EGLN3RXRA | |
| SCHEMBL6339239 | 0.81 | GRM5 (0.39) | MELKGRM5RXRAGRIN1GRIN2B | |
| SCHEMBL6328488 | 0.77 | HTT (0.41) | RXRAGRIN1GRIN2BLMNACYP2C9 | |
| SCHEMBL6330405 | 0.76 | CHRNB2 (0.43) | MELKEGLN1EGFR | |
| SCHEMBL6332341 | 0.74 | GRM5 (0.42) | GRM5EGFR | |
| SCHEMBL2432983 | 0.72 | SMN1; SMN2 (0.47) | RXRAGRIN1GRIN2BLMNACYP2C9 | |
| SCHEMBL6227834 | 0.72 | KDM4E (0.55) | LMNATSHRAPEX1 | |
| SCHEMBL4764816 | 0.71 | MRGPRX4 (0.41) | KCNH2LMNASMN1; SMN2 | |
| SCHEMBL12016065 | 0.70 | LMNA (0.46) | CHRM2GRM5KCNH2LMNACYP2C9 | |
| SCHEMBL14619120 | 0.70 | KMT2A (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-27 | — | — | US | disclosed |
| EP-1370140-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002028182-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | DDT, GSTM1, CYP4X1 | MELK 2138/4885CHRM2 30/4885GRM5 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.