Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330405 | 0.84 | CHRNB2 (0.43) | CHRNB2CHRNA4NPC1POLBRAB9A | |
| SCHEMBL6329779 | 0.77 | CHRNB2 (0.45) | CHRNB2CHRNA4NPC1POLBRAB9A | |
| SCHEMBL7266190 | 0.74 | GRM5 (0.39) | RAB9AEGLN1MEN1KMT2AALDH1A1 | |
| SCHEMBL6597369 | 0.74 | GRM5 (0.57) | NPC1POLBRAB9AEGLN1MEN1 | |
| SCHEMBL6596154 | 0.72 | GRM5 (0.40) | NPC1POLBRAB9AMEN1KMT2A | |
| SCHEMBL6598860 | 0.70 | MEN1 (0.50) | NPC1POLBRAB9AMEN1KMT2A | |
| SCHEMBL29679102 | 0.70 | MEN1 (0.50) | NPC1POLBRAB9AMEN1KMT2A | |
| SCHEMBL22241820 | 0.69 | PDE10A (0.53) | NPC1POLBRAB9AMEN1KMT2A | |
| SCHEMBL4764816 | 0.68 | MRGPRX4 (0.41) | NPC1POLBRAB9AMEN1KMT2A | |
| SCHEMBL6814044 | 0.67 | ALDH1A1 (0.38) | POLBMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248739-A1 | Pyridylpropynyloxyphenyl derivatives for use as herbicides | SCHAETZER JURGEN (CH) | 2004-12-09 | — | — | US | disclosed |
| EP-1414301-A1 | PYRIDYLPROPYNYLOXYPHENYL DERIVATIVES FOR USE AS HERBICIDES | Syngenta Participations AG (CH) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013247-A1 | PYRIDYLPROPYNYLOXYPHENYL DERIVATIVES FOR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248739-A1 | Pyridylpropynyloxyphenyl derivatives for use as herbicides | DDT, CYP4X1, CHRM1 | CHRNB2 1200/4885CHRNA4 605/4885NPC1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.