Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16536866 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8693732 | 0.77 | TDP1 (0.43) | ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL7719268 | 0.76 | RIPK1 (0.38) | ALDH1A1ALOX15TSHR | |
| SCHEMBL7447002 | 0.75 | — | — | |
| SCHEMBL8946202 | 0.74 | HRH3 (0.35) | CYP3A4 | |
| SCHEMBL16537134 | 0.73 | CHRNB2 (0.40) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8825019 | 0.73 | CHRNB2 (0.40) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL7719269 | 0.73 | — | — | |
| SCHEMBL8759242 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5888379 | 0.71 | ALDH1A1 (0.44) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6889735-B2 | Pneumatic tire having a rubber component containing a dendrimer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-05-10 | — | — | US | disclosed |
| US-20040020576-A1 | Pneumatic tire having a rubber component containing a dendrimer | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-02-05 | — | — | US | disclosed |
| US-20020068796-A1 | Pneumatic tire having a rubber component containing a dendrimer | FRANK UWE ERNST (DE) | 2002-06-06 | — | — | US | disclosed |
| EP-1177919-A2 | A pneumatic tire having a rubber component containing a dendrimer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5276110-A | Highly regular multi-arm star polymers | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1994-01-04 | — | — | US | disclosed |