Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931546 | 0.99 | TSHR (0.42) | CYP2D6TSHRSMN1; SMN2POLBPTPN1 | |
| SCHEMBL15534783 | 0.91 | PTPN1 (0.43) | CYP2D6TSHRSMN1; SMN2PTPN1PTPN6 | |
| SCHEMBL1539831 | 0.80 | PTPN1 (0.43) | CYP2D6TSHRSMN1; SMN2PTPN1PTPN6 | |
| SCHEMBL6330115 | 0.79 | PTGS2 (0.35) | CYP2D6PTPN1PTPN6PTGS2NFE2L2 | |
| SCHEMBL11741666 | 0.78 | TSHR (0.60) | CYP2D6TSHRSMN1; SMN2POLBPTPN1 | |
| SCHEMBL28377435 | 0.78 | PTPN1 (0.44) | CYP2D6SMN1; SMN2PTPN1PTPN6PTGS2 | |
| SCHEMBL29990836 | 0.78 | PTPN1 (0.44) | CYP2D6SMN1; SMN2PTPN1PTPN6PTGS2 | |
| SCHEMBL28400808 | 0.77 | TSHR (0.40) | CYP2D6TSHRSMN1; SMN2POLBPTPN1 | |
| SCHEMBL1170845 | 0.77 | MAOA (0.44) | SMN1; SMN2PTPN1PTPN6PTGS2HDAC1 | |
| SCHEMBL30835513 | 0.77 | PTPN1 (0.40) | TSHRPTPN1PTPN6PTGS2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137117-A1 | Composition containing an optical brightener and a semi-crystalline polymer | L'OREAL (FR) | 2005-06-23 | — | — | US | claimed |
| US-20050137117-A1 | Composition containing an optical brightener and a semi-crystalline polymer | L'OREAL (FR) | 2005-06-23 | — | — | US | disclosed |