Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329391 | 0.96 | KMT2A (0.40) | KMT2ALMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL6332546 | 0.93 | CYP2D6 (0.41) | KMT2ALMNAPOLBL3MBTL1ALDH1A1 | |
| Fumaric Acid SCHEMBL6332303 | 0.85 | NOS2 (0.50) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| Fumaric Acid SCHEMBL6332308 | 0.85 | NOS2 (0.50) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6338041 | 0.85 | NOS2 (0.48) | KMT2ALMNAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6332398 | 0.85 | NOS2 (0.47) | KMT2ALMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL6330128 | 0.82 | VCAM1 (0.39) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6338279 | 0.80 | NOS2 (0.47) | KMT2ALMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL6337105 | 0.80 | NOS2 (0.56) | LMNAALDH1A1TBXA2RHPGDCYP2D6 | |
| Oxalic Acid SCHEMBL6328020 | 0.80 | NOS2 (0.46) | KMT2ALMNAL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900243-B2 | Phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2005-05-31 | — | — | US | disclosed |
| EP-1263715-B1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| US-20030065174-A1 | Novel phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065174-A1 | Novel phenylheteroalkylamine derivatives | OPRK1, NOS2, OPRM1 | KMT2A 2640/4885LMNA 3253/4885POLB 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.